The JAK2 inhibitor AG490 regulates the Treg/Th17 balance and alleviates DSS‐induced intestinal damage in IBD rats
Author:
Affiliation:
1. Department of Pediatrics Shengjing Hospital of China Medical University Shenyang China
2. Department of Neonatology The First People’s Hospital of Lianyungang/The Affiliated Lianyungang Hospital of Xuzhou Medical University Lianyungang China
Funder
the Natural Science Foundation of Liaoning Province, China
Publisher
Wiley
Subject
Physiology (medical),Pharmacology,Physiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/1440-1681.13311
Reference35 articles.
1. The immunological and genetic basis of inflammatory bowel disease
2. IL-21 regulates experimental colitis by modulating the balance between Treg and Th17 cells
3. The balance of intestinal Foxp3+regulatory T cells and Th17 cells and its biological significance
4. Metformin Ameliorates Inflammatory Bowel Disease by Suppression of the STAT3 Signaling Pathway and Regulation of the between Th17/Treg Balance
5. Aberrant frequency of IL‐10‐producing B cells and its association with the balance of Treg/Th17 in children with inflammatory bowel disease;Zhu XM;Pharmazie,2015
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