Fragrance allergens in cosmetic products marketed for children in Denmark-Reference-Cited by-同舟云学术

Fragrance allergens in cosmetic products marketed for children in Denmark

Published:2023-08-17 Issue:5 Volume:89 Page:374-381
ISSN:0105-1873
Container-title:Contact Dermatitis
language:en
Short-container-title:Contact Dermatitis

Author:

Botvid Sofia¹²^ORCID,Simonsen Anne Birgitte¹²,Jørgensen Claus³,Müller Stine³,Kirkeby Christel Søgaard³,Christensen Anne Beck³,Johansen Jeanne Duus¹²^ORCID

Affiliation:

1. The National Allergy Research Centre (Videncenter for Allergi), Department of Allergy, Dermatology and Venerology Copenhagen University Hospital Herlev‐Gentofte, Gentofte Hospital Hellerup Denmark

2. Faculty of Health and Medical Sciences, Department of Clinical Medicine University of Copenhagen Copenhagen N Denmark

3. The Danish Consumer Council THINK Chemicals (Forbrugerrådet TÆNK Kemi) Copenhagen N Denmark

Abstract

AbstractBackgroundFragrances are among the most common contact allergens in children. Cosmetic products are the most frequent source of skin exposure.ObjectiveTo investigate exposure to fragrance allergens among Danish children, based on a sample of 1179 cosmetic products marketed for children.MethodsInformation regarding cosmetic products marketed to children was obtained using a non‐profit smartphone application registry, with data from December 2015 to November 2022.ResultsThe number of validated products was 26 537, of which 1349 marketed for children. After elimination of duplicates, 1179 (4.4%) individual products remained. The majority 53.8% (634/1179) of the products were fragranced. The highest frequency of declared fragrances was found in ‘Facial care’‐products: 93.0% (80/86), of which 97.7% were lip balms. The highest number of labelled fragrances in one single product (n = 16) was found in a baby perfume. Fragrance mix I (FMI) or II (FMII) allergens were found in 25.3% (298/1179) of the products. Limonene and linalool were the two most frequently labelled fragrance allergens.ConclusionChildren can be exposed to a vast number of fragrance allergens from scented cosmetic products. Allergens from FM I and FMII are widely used in cosmetic products marketed to children. Patch testing with FMI and FMII remains relevant in children.

Publisher

Wiley

Subject

Dermatology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cod.14397

Reference51 articles.

1. IFRA.Transparency List. Accessed October 13 2022https://ifrafragrance.org/priorities/ingredients/ifra‐transparency‐list

2. Categorization of fragrance contact allergens for prioritization of preventive measures: clinical and experimental data and consideration of structure-activity relationships

3. Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products (recast) (Text with EEA relevance). Accessed June 13 2023https://www.legislation.gov.uk/eur/2009/1223/contents

4. Characteristics of patients patch tested in the European Surveillance System on Contact Allergies (ESSCA) network, 2009-2012