Safety and efficacy of BAY 94-9027, a prolonged-half-life factor VIII

Author:

Reding M. T.1,Ng H. J.2,Poulsen L. H.3,Eyster M. E.4,Pabinger I.5,Shin H.-J.6,Walsch R.7,Lederman M.8,Wang M.8,Hardtke M.9,Michaels L. A.8

Affiliation:

1. University of Minnesota Medical Center; Minneapolis MN USA

2. Department of Haematology; Singapore General Hospital; Singapore

3. Centre for Haemophilia and Thrombosis; Aarhus University Hospital; Aarhus Denmark

4. Penn State Hershey Medical Center; Hershey PA USA

5. Division of Haematology and Haemostaseology; Department of Medicine I; Medical University of Vienna; Vienna Austria

6. Division of Hematology-Oncology; Department of Internal Medicine; School of Medicine, Medical Research Institute; Pusan National University Hospital; Busan Korea

7. Bayer Vital GmbH; Leverkusen Germany

8. Bayer; Whippany NJ USA

9. Bayer Pharma AG; Berlin Germany

Funder

Bayer Pharma AG, Leverkusen, Germany

Publisher

Wiley

Subject

Hematology

Reference28 articles.

1. Prophylaxis versus episodic treatment to prevent joint disease in boys with severe hemophilia;Manco-Johnson;N Engl J Med,2007

2. A randomized clinical trial of prophylaxis in children with hemophilia A (the ESPRIT Study);Gringeri;J Thromb Haemost,2011

3. National Hemophilia Foundation. Medical and Scientific Advisory Council (MASAC) recommendations concerning prophylaxis (regular administration of clotting factor concentrate to prevent bleeding) https://www.hemophilia.org/sites/default/files/document/files/241Prophylaxis.pdf

4. Guidelines for the management of hemophilia;Srivastava;Haemophilia,2013

5. Practice patterns in haemophilia A therapy - global progress towards optimal care;Geraghty;Haemophilia,2006

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