Cilengitide restrains the osteoclast-like bone resorbing activity of myeloma plasma cells

Author:

Tucci Marco1,Stucci Stefania1,Felici Claudia1,Cafforio Paola1,Resta Leonardo2,Rossi Roberta2,Silvestris Franco1

Affiliation:

1. Department of Biomedical Sciences and Human Oncology; University of Bari ‘Aldo Moro’; Bari Italy

2. Department of Emergency and Organ Transplantation; University of Bari ‘Aldo Moro’; Bari Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Wiley

Subject

Hematology

Reference39 articles.

1. Mechanical control of integrin-mediated adhesion and signaling;Boettiger;Current Opinion in Cell Biology,2012

2. Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma;Breitkreutz;Leukemia,2008

3. Cilengitide inhibits metastatic bone colonization in a nude rat model;Bretschi;Oncology Reports,2011

4. Anti-integrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin;Brooks;J Clin Invest,1995

5. The involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model;Caers;Br J Hematol,2006

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