Biological and clinical significance of the intratumour heterogeneity of PTEN protein expression and the corresponding molecular abnormalities of thePTENgene in glioblastomas-Reference-Cited by-同舟云学术

Biological and clinical significance of the intratumour heterogeneity of PTEN protein expression and the corresponding molecular abnormalities of thePTENgene in glioblastomas

Published:2014-09-25 Issue:6 Volume:40 Page:736-746
ISSN:0305-1846
Container-title:Neuropathology and Applied Neurobiology
language:en
Short-container-title:Neuropathol Appl Neurobiol

Author:

Idoate Miguel A.¹,Echeveste Jose¹,Diez-Valle Ricardo²,Lozano Maria Dolores¹,Aristu José³

Affiliation:

1. Pathology; University Hospital and Faculty of Medicine; University of Navarra; Pamplona Spain

2. Neurosurgery; University Hospital and Faculty of Medicine; University of Navarra; Pamplona Spain

3. Radiotherapy; University Hospital and Faculty of Medicine; University of Navarra; Pamplona Spain

Funder

Navarra Government

Publisher

Wiley

Subject

Physiology (medical),Neurology (clinical),Neurology,Histology,Pathology and Forensic Medicine

Reference26 articles.

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3. Receptor tyrosine kinase genes amplified in glioblastoma exhibit a mutual exclusivity in variable proportions reflective of individual tumor heterogeneity;Little;Cancer Res,2012

4. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing;Gerlinger;N Engl J Med,2012

5. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors;Mellinghoff;N Engl J Med,2005

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