On Frequency and Probability Weights: An In‐Depth Look at Duelling Weights

Author:

Lin Tuo1ORCID,Chen Ruohui2,Liu Jinyuan3,Wu Tsungchin4,Gui Toni T.1,Li Yangyi5,Huang Xinyi4,Yang Kun4,Chen Guanqing6,Chen Tian7,Strong David R.8,Messer Karen4,Tu Xin M.4

Affiliation:

1. Department of Biostatistics University of Florida Gainesville FL USA

2. Division of Biostatistics Northwestern University Feinberg School of Medicine Chicago IL USA

3. Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA

4. Division of Biostatistics and Bioinformatics, Herbert Wertheim School of Public Health and Human Longevity Science University of California San Diego, La Jolla CA USA

5. School of Mathematical and Statistical Sciences Clemson University Clemson SC USA

6. Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center Harvard Medical School Boston MA USA

7. Takeda Pharmaceuticals Cambridge MA USA

8. Joint Doctoral Program, Public Health, Herbert Wertheim School of Public Health and Human Longevity Science University of California San Diego, La Jolla CA USA

Abstract

SummaryProbability weights have been widely used in addressing selection bias arising from a variety of contexts. Common examples of probability weights include sampling weights, missing data weights, and propensity score weights. Frequency weights, which are used to control for varying variabilities of aggregated outcomes, are both conceptually and analytically different from probability weights. Popular software such as R, SAS and STATA support both types of weights. Many users, including professional statisticians, become bewildered when they see identical estimates, but different standard errors and ‐values when probability weights are treated as frequency weights. Some even completely ignore the difference between the two types of weights and treat them as the same. Although a large body of literature exists on each type of weights, we have found little, if any, discussion that provides head‐to‐head comparisons of the two types of weights and associated inference methods. In this paper, we unveil the conceptual and analytic differences between the two types of weights within the context of parametric and semi‐parametric generalised linear models (GLM) and discuss valid inference for each type of weights. To the best of our knowledge, this is the first paper that looks into such differences by identifying the conditions under which the two types of weights can be treated the same analytically and providing clear guidance on the appropriate statistical models and inference procedures for each type of weights. We illustrate these considerations using real study data.

Publisher

Wiley

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3. Centers for Disease Control and Prevention (CDC) N.2010.National health and nutrition examination survey data. Hyattsville MD: US Department of Health and Human Services Centers for Disease Control and Prevention.

4. Bootstrap consistency for general semiparametric m‐estimation;Cheng G.;The Ann. Stat.,2010

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