A genome‐wide association study of the frailty index highlights brain pathways in ageing

Author:

Atkins Janice L.1ORCID,Jylhävä Juulia2,Pedersen Nancy L.23,Magnusson Patrik K.2,Lu Yi2,Wang Yunzhang2,Hägg Sara2ORCID,Melzer David14,Williams Dylan M.25,Pilling Luke C.14ORCID

Affiliation:

1. Epidemiology and Public Health Group University of Exeter Medical School Exeter UK

2. Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden

3. Department of Psychology University of Southern California Los Angeles CA USA

4. Center on Aging University of Connecticut Farmington CT USA

5. MRC Unit for Lifelong Health and Ageing at UCL University College London London UK

Funder

Medical Research Council

Vetenskapsrådet

National Institutes of Health

Karolinska Institutet

Publisher

Wiley

Subject

Cell Biology,Aging

Reference52 articles.

1. Frailty in NHANES: Comparing the frailty index and phenotype

2. Neurexins and neuroligins: synapses look out of the nervous system

3. Central adiposity and the overweight risk paradox in aging: follow-up of 130,473 UK Biobank participants

4. Broad Institute of MIT and Harvard(2016).Broad Institute TCGA Genome Data Analysis Center. Correlation between mRNA expression and DNA methylation. Broad Institute of MIT and Harvard.

5. Broad Institute RICOPILI: Rapid Imputation and COmputational PIpeLIne for Genome‐Wide Association Studies. Available at:https://sites.google.com/a/broadinstitute.org/ricopili/home.

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