Interrogation of CYP 2D6 Structural Variant Alleles Improves the Correlation Between CYP 2D6 Genotype and CYP 2D6‐Mediated Metabolic Activity-Reference-Cited by-同舟云学术

Interrogation of CYP 2D6 Structural Variant Alleles Improves the Correlation Between CYP 2D6 Genotype and CYP 2D6‐Mediated Metabolic Activity

Published:2019-10-25 Issue:1 Volume:13 Page:147-156
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Dalton Rachel¹,Lee Seung‐been²,Claw Katrina G.³,Prasad Bhagwat³,Phillips Brian R.³,Shen Danny D.³,Wong Lai Hong²,Fade Mitch²,McDonald Matthew G.⁴,Dunham Maitreya J.²,Fowler Douglas M.²,Rettie Allan E.⁴,Schuetz Erin⁵,Thornton Timothy A.⁶,Nickerson Deborah A.²,Gaedigk Andrea⁷,Thummel Kenneth E.³,Woodahl Erica L.¹

Affiliation:

1. Department of Biomedical and Pharmaceutical Sciences University of Montana Missoula Montana USA

2. Departments of Genome Sciences University of Washington Seattle Washington USA

3. Department of Pharmaceutics University of Washington Seattle Washington USA

4. Department of Medicinal Chemistry University of Washington Seattle Washington USA

5. Department of Pharmaceutical Sciences St. Jude Children's Research Hospital Memphis Tennessee USA

6. Department of Biostatistics University of Washington Seattle Washington USA

7. Division of Clinical Pharmacology, Toxicology, & Therapeutic Innovation Children's Mercy Kansas City and School of Medicine University of Missouri‐Kansas City Kansas City Missouri USA

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12695

Reference47 articles.

1. Pharmacogenetics, Drug-Metabolizing Enzymes, and Clinical Practice

2. Prediction of drug response and adverse drug reactions: From twin studies to Next Generation Sequencing

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4. Prediction of CYP2D6 phenotype from genotype across world populations

5. Accurately genotyping CYP2D6: not for the faint of heart

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