Assessing replicability with the sceptical p$$ p $$‐value: Type‐I error control and sample size planning

Author:

Micheloud Charlotte12,Balabdaoui Fadoua3,Held Leonhard12

Affiliation:

1. Epidemiology, Biostatistics and Prevention Institute (EBPI) University of Zurich Zurich Switzerland

2. Center for Reproducible Science (CRS) University of Zurich Zurich Switzerland

3. Seminar für Statistik ETH Zurich Zurich Switzerland

Abstract

We study a statistical framework for replicability based on a recently proposed quantitative measure of replication success, the sceptical ‐value. A recalibration is proposed to obtain exact overall Type‐I error control if the effect is null in both studies and additional bounds on the partial and conditional Type‐I error rate, which represent the case where only one study has a null effect. The approach avoids the double dichotomization for significance of the two‐trials rule and has larger project power to detect existing effects over both studies in combination. It can also be used for power calculations and requires a smaller replication sample size than the two‐trials rule for already convincing original studies. We illustrate the performance of the proposed methodology in an application to data from the Experimental Economics Replication Project.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

Publisher

Wiley

Subject

Statistics, Probability and Uncertainty,Statistics and Probability

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