The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial-Reference-Cited by-同舟云学术

The effect of ibuprofen sustained release oral premedication on intraoperative and postoperative pain: A randomised clinical trial

Published:2024-03-25 Issue:2 Volume:50 Page:227-236
ISSN:1329-1947
Container-title:Australian Endodontic Journal
language:en
Short-container-title:Aust Endodontic J

Author:

Hossam Mariam Ahmed¹,El Baz Alaa Abdelsalam¹,Kwak Sang Won²,Kim Hyeon‐Cheol²^ORCID,Abielhassan Mohamed Mohsen¹^ORCID

Affiliation:

1. Department of Endodontics, Faculty of Dentistry Cairo University Giza Egypt

2. Department of Conservative Dentistry, School of Dentistry Dental Research Institute, Dental and Life Science Institute, Pusan National University Yangsan Korea

Abstract

AbstractThe aim of this study was to assess the effect of ibuprofen sustained release (SR) oral premedication on the efficacy of buccal infiltration (BI) with intraoperative and postoperative pain after single‐visit root canal treatment. Sixty patients diagnosed with symptomatic irreversible pulpitis and apical periodontitis in mandibular molar were divided into two groups. Group SR received ibuprofen SR 800 mg and group PL received placebo capsule 1 h before 3.6 mL articaine BI injection. Pain was recorded using a modified visual analogue scale and postoperatively at intervals 6, 24 and 48 h. Group SR showed a significantly higher anaesthetic success rate (73.3%) compared to group PL (46.7%) (p < 0.05). Intraoperative and postoperative pain was significantly higher in group PL compared to group SR (p < 0.05). Premedication of ibuprofen SR improved the efficacy of primary BI in mandibular molars with symptomatic irreversible pulpitis and decreased postoperative pain at 6 and 48 h.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/aej.12839

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