Should Aprotinin be reconsidered for use in pediatric surgery?

Author:

Goobie Susan1

Affiliation:

1. Anesthesiology, Perioperative and Pain Medicine; Boston Children's Hospital; Boston MA USA

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine,Pediatrics, Perinatology and Child Health

Reference32 articles.

1. Antifibrinolytic therapy: new data and new concepts;Levy;Lancet,2010

2. Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery;Graham;J Thorac Cardiovasc Surg,2012

3. Aprotinin protects the cerebral microcirculation during cardiopulmonary bypass;Ishibashi;Perfusion,2009

4. Overview of clinical efficacy and safety of pharmacologic strategies for blood conservation;Levy;Am J Health Syst Pharm,2005

5. U.S. Food and Drug Administration Information for healthcare professionals: aprotinin injection (marketed as trasylol) 2006 http://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020304s022lbl.pdf

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