Superficial basal cell carcinoma mimicking Bowen's disease: Diagnosis with noninvasive imaging

Author:

Chen Ke‐Jun12ORCID,Wang Zi‐Yi12ORCID,Han Yang12,Cui Yong2ORCID

Affiliation:

1. Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China

2. Department of Dermatology China‐Japan Friendship Hospital Beijing China

Abstract

AbstractBackgroundSuperficial basal cell carcinoma (SBCC) is the rare subtype of basal cell carcinoma (BCC). BCC occurs in exposed areas such as the head and face, SCBB prone to form in trunk. Due to the manifestation of erythema and desquamation, it is prone to misdiagnosed as Bowen's disease in clinica.Materials and methodsA 68‐year‐old female presented with coin‐sized erythema located on the lower abdomen for 5 years. Histopathological examination was performed, and results informed the diagnosis of SBCC. Lesions were detected by dermoscopy, reflectance confocal microscopy (RCM) and multiphoton microscopy (MPM).ResultsDermoscopy revealed yellow–red background with more dendritic and linear proliferating vessels and more blue‐gray nonaggregated dots structures. RCM displayed streaming of stratum spinosum, tortuous dilated vessels, highlighted inflammatory cells, and medium refraction round and oval tumor cell masses. MPM showed epidermal cells in polar arrangement, increased cell spacing, disorganized stratum granulosum and elastic fibers are gathered in clusters.ConclusionWe described a case of SBCC detected by dermoscopy, RCM and MPM. Noninvasive imaging features may provide a potentially tools in recognition and differentiation of SBCC.

Publisher

Wiley

Subject

Dermatology

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