Effect of capmatinib on the pharmacokinetics of substrates of CYP3A (midazolam) and CYP1A2 (caffeine) in patients with MET‐dysregulated solid tumours-Reference-Cited by-同舟云学术

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Effect of capmatinib on the pharmacokinetics of substrates of CYP3A (midazolam) and CYP1A2 (caffeine) in patients with MET‐dysregulated solid tumours

Published:2022-10-17 Issue:3 Volume:89 Page:1046-1055
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Brit J Clinical Pharma

Author:

Chen Xinhui¹,Isambert Nicolas²,López‐López Rafael³,Giovannini Monica⁴,Pognan Nathalie⁵,Kapoor Shruti⁴,Quinlan Michelle⁴,You Benoit⁶,Cui Xiaoming¹^ORCID,Rahmanzadeh Gholamreza⁷,Mau‐Sorensen Morten⁸^ORCID

Affiliation:

1. Novartis Institutes for BioMedical Research East Hanover New Jersey USA

2. Department of Medical Oncology Centre Georges‐François Leclerc Dijon France

3. Medical Oncology University Clinical Hospital‐IDIS‐CIBERONC Santiago de Compostela Spain

4. Global Drug Development Novartis Services Inc. Princeton New Jersey USA

5. Global Drug Development Novartis Pharma S.A.S. Rueil‐Malmaison France

6. Medical Oncology, Institut de Cancérologie des Hospices Civils de Lyon Université Claude Bernard Lyon 1, Cicly, Gineco Lyon France

7. Novartis Pharma AG Basel Switzerland

8. Department of Oncology Copenhagen University Hospital, Rigshospitalet Copenhagen Denmark

Funder

Novartis Pharmaceuticals Corporation

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcp.15544

Reference27 articles.

1. Gene amplification in gastric and esophageal adenocarcinomas;Houldsworth J;Cancer Res,1990

2. The HGF Receptor c-Met Is Overexpressed in Esophageal Adenocarcinoma

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