Melatonin-mediated miR-526b-3p and miR-590-5p upregulation promotes chondrogenic differentiation of human mesenchymal stem cells

Author:

Wu Zizhao1ORCID,Qiu Xianjian1,Gao Bo1,Lian Chengjie2,Peng Yan1,Liang Anjing1,Xu Caixia3,Gao Wenjie24,Zhang Liangming5,Su Peiqiang26ORCID,Rong Limin5,Huang Dongsheng1ORCID

Affiliation:

1. Department of Orthopedics; Sun Yat-sen Memorial Hospital of Sun Yat-sen University; Guangzhou Guangdong China

2. Department of Orthopedics; The First Affiliated Hospital of Sun Yat-sen University; Guangzhou Guangdong China

3. Research Centre for Translational Medicine; The First Affiliated Hospital of Sun Yat-sen University; Guangzhou Guangdong China

4. Department of Spine Surgery; Xi'an Honghui Hospital; Xi'an Jiaotong University; Xi'an China

5. Department of Spine Surgery; The Third Affiliated Hospital of Sun Yat-Sen University; Guangzhou China

6. Guangdong Provincial Key Laboratory of Orthopedics and Traumatology; The First Affiliated Hospital of Sun Yat-sen University; Guangzhou Guangdong China

Funder

Natural Science Basic Research Plan in Shanxi Province of China

China Postdoctoral Science Foundation

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Wiley

Subject

Endocrinology

Reference56 articles.

1. Stem cells and cartilage development: complexities of a simple tissue;Hollander;Stem Cells,2010

2. Mesenchymal stem cells display different gene expression profiles compared to hyaline and elastic chondrocytes;Zhai;Int J Clin Exp Med,2011

3. Mesenchymal stem cells in bone development, bone repair, and skeletal regeneration therapy;Bruder;J Cell Biochem,1994

4. Multipotential differentiation of adipose tissue-derived stem cells;Strem;Keio J Med,2005

5. Human adipose-derived stem cells contribute to chondrogenesis in coculture with human articular chondrocytes;Hildner;Tissue Eng Part A,2009

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