Clinical significance of CYP2C9-status guided valproic acid therapy in children
Author:
Affiliation:
1. 2nd Department of Pediatrics; Semmelweis University; Budapest Hungary
2. Research Center for Natural Sciences; Hungarian Academy of Sciences; Budapest Hungary
3. Heim Pál Children's Hospital; Budapest Hungary
Funder
Hungarian Research Fund
National Development Agency and the European Union
Publisher
Wiley
Subject
Clinical Neurology,Neurology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/epi.13011/fullpdf
Reference33 articles.
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3. Valproic acid hepatic fatalities. III. U.S. experience since 1986;Bryant;Neurology,1996
4. Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes;Ho;Pharmacogenomics J,2003
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