High-Content Analysis in Toxicology: Screening Substances for Human Toxicity Potential, Elucidating Subcellular Mechanisms andIn VivoUse as Translational Safety Biomarkers-Reference-Cited by-同舟云学术

High-Content Analysis in Toxicology: Screening Substances for Human Toxicity Potential, Elucidating Subcellular Mechanisms andIn VivoUse as Translational Safety Biomarkers

Published:2014-04-15 Issue:1 Volume:115 Page:4-17
ISSN:1742-7835
Container-title:Basic & Clinical Pharmacology & Toxicology
language:en
Short-container-title:Basic Clin Pharmacol Toxicol

Author:

O'Brien Peter J.¹²

Affiliation:

1. Veterinary Science Centre; University College Dublin; Dublin 4 Ireland

2. Advanced Diagnostics Laboratory; Park West Enterprise Centre; Dublin 12 Ireland

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcpt.12227/fullpdf

Reference50 articles.

1. Addressing toxicity risk when designing and selecting compounds in early drug discovery;Segall;Drug Discovery Today,2014

2. Evaluation of the characteristics of safety withdrawal of prescription drugs from worldwide pharmaceutical markets-1960-1999;Fung;Drug Inf J,2001

3. The significance of mitochondrial toxicity testing in drug development;Dykens;Drug Discovery Today,2007

4. Drug-induced hepatotoxicity;Lee;N Engl J Med,2003

5. Concordance of the toxicity of pharmaceuticals in humans and in animals;Olson;Regul Toxicol Pharmacol,2000

Cited by 74 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Integrating high-throughput phenotypic profiling and transcriptomic analyses to predict the hepatosteatosis effects induced by per- and polyfluoroalkyl substances;Journal of Hazardous Materials;2024-05

2. Hazard assessment of nanomaterials using in vitro toxicity assays: Guidance on potential assay interferences and mitigating actions to avoid biased results;Nano Today;2024-04

3. Automated Analysis of Structural Alterations in Microscopic Cellular Images for Identification of Cytotoxicity Using Texture Feature Descriptors;Lecture Notes in Mechanical Engineering;2024

4. High content screening in toxicology;Public Health and Toxicology Issues Drug Research, Volume 2;2024

5. Unveiling hepatotoxicity distinction of coumarin-related compounds from glycosides to aglycones in Fructus Psoraleae by integrating UPLC-Q-TOF-MS and high content analysis;Journal of Ethnopharmacology;2023-10