A novel score for predicting 1‐year mortality of intensive care patients

Author:

Pietiläinen Laura12ORCID,Hästbacka Johanna3ORCID,Bäcklund Minna4,Selander Tuomas5ORCID,Reinikainen Matti12ORCID

Affiliation:

1. Department of Anaesthesiology and Intensive Care Kuopio University Hospital Kuopio Finland

2. University of Eastern Finland Kuopio Finland

3. Department of Anesthesia and Intensive Care Tampere University Hospital, and Tampere University Tampere Finland

4. Division of Intensive Care Medicine, Department of Perioperative, Intensive Care and Pain Medicine University of Helsinki and Helsinki University Hospital Helsinki Finland

5. Science Service Center Kuopio University Hospital Kuopio Finland

Abstract

AbstractBackgroundWe aimed to develop a simple scoring table for predicting probability of death within 1‐year after admission to an intensive care unit. We analysed data on emergency admissions from the nationwide Finnish intensive care quality registry.MethodsWe included first admissions of adult patients with data available on 1‐year vital status (dead or alive) and all five variables included in a premorbid functional status score, which is the number of activities the person can manage independently of the following five: get out of bed, move indoors, dress, climb stairs and walk 400 m. We analysed data on patient characteristics and admission‐associated factors from 2012 to 2014 to find predictors of 1‐year mortality and to develop a score for predicting probability of death. We tested the performance of this score in data from 2015. We assessed the 1‐year functional status score of survivors with data available.ResultsOut of 25,261 patients, 20,628 (81.7%) patients were able to perform all five functional activities independently prior to the intensive care unit admission. At 1‐year post admission, 19,625 (77.7%) patients were alive. 1‐year functional status score was known for 11,011 patients and 8970 (81.5%) patients achieved functional status score 5, managing all five activities independently. The score based on age, sex, preceding functional status, type of intensive care unit admission, severity of acute illness and the most significant diagnoses predicted 1‐year mortality with an area under the receiver operating characteristic curve 0.78 (95% CI, 0.76–0.79). The calibration of our prediction model was good, with calibration intercept −0.01 (−0.07 to 0.05) and calibration slope 0.96 (0.90 to 1.02).ConclusionOur score based on data available at intensive care unit admission predicted 1‐year mortality with fairly good discrimination. Most survivors achieved good functional recovery.

Funder

Kuopion Yliopistollinen Sairaala

Publisher

Wiley

Subject

Anesthesiology and Pain Medicine,General Medicine

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