Elevated fetal haemoglobin is a predictor of better outcome in MDS/AML patients receiving 5-aza-2′-deoxycytidine (Decitabine)

Author:

Lübbert Michael1,Ihorst Gabriele2,Sander Philipp N.1,Bogatyreva Ljudmila13,Becker Heiko1,Wijermans Pierre W.4,Suciu Stefan5,Bissé Emmanuel6,Claus Rainer1

Affiliation:

1. Division of Haematology, Oncology and Stem Cell Transplantation; Faculty of Medicine; University of Freiburg; Freiburg Germany

2. Clinical Trials Unit; University of Freiburg Medical Centre; Freiburg Germany

3. Institute for Medical Biometry and Statistics; Faculty of Medicine and Medical Centre - University of Freiburg; Freiburg Germany

4. Department of Haematology; Haga Hospital; The Hague The Netherlands

5. EORTC Headquarters; Brussels Belgium

6. Institute for Laboratory Diagnostics; University of Freiburg; Freiburg Germany

Funder

California Department of Fish and Game

Wilhelm Sander-Stiftung

European Organisation for Research and Treatment of Cancer

Deutsche Krebshilfe

Publisher

Wiley

Subject

Hematology

Reference29 articles.

1. Prognosis of older patients with acute myeloid leukemia receiving either induction or noncurative treatment: a single-center retrospective study;Behringer;Annals of Hematology,2003

2. Proposals for the classification of the acute leukaemias French-American-British (FAB) Co-operative Group;Bennett;British Journal of Haematology,1976

3. High-performance liquid chromatographic separation of human haemoglobins. Simultaneous quantitation of foetal and glycated haemoglobins;Bissé;Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences,1988

4. Report of an international working group to standardize response criteria for myelodysplastic syndromes;Cheson;Blood,2000

5. Revised Recommendations of the International Working Group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia;Cheson;Journal of Clinical Oncology,2003

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