Intravitreous treatment of severe ocular von Hippel–Lindau disease using a combination of the VEGF inhibitor, ranibizumab and PDGF inhibitor, E10030 : Results from a phase 1/2 clinical trial

Author:

Hwang Christopher K.1ORCID,Chew Emily Y.1,Cukras Catherine A.1,Keenan Tiarnan D. L.1,Wong Wai T.2,Linehan W. Marston3,Chittiboina Prashant4,Pacak Karel5,Wiley Henry E.1

Affiliation:

1. Division of Epidemiology and Clinical Applications National Eye Institute, National Institutes of Health Bethesda Maryland USA

2. Section on Neuron‐Glia Interactions in Retinal Disease National Eye Institute, National Institutes of Health Bethesda Maryland USA

3. Urologic Oncology Branch National Cancer Institute, National Institutes of Health Bethesda Maryland USA

4. Neurosurgery Unit for Pituitary and Inheritable Diseases National Institute of Neurological Disorders and Stroke, National Institutes of Health Bethesda Maryland USA

5. Section on Medical Neuroendocrinology Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health Bethesda Maryland USA

Funder

Heed Ophthalmic Foundation

National Institutes of Health

Publisher

Wiley

Subject

Ophthalmology

Reference39 articles.

1. Clinical Features and Natural History of von Hippel-Lindau Disease

2. von Hippel–Lindau Disease

3. Ocular manifestations of von Hippel‐Lindau disease: clinical and genetic investigations;Chew EY;Trans Am Ophthalmol Soc,2005

4. MANAGEMENT OF RETINAL HEMANGIOBLASTOMA IN VON HIPPEL–LINDAU DISEASE

5. Juxtapapillary capillary hemangiomas

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