Acute leukoencephalopathy possibly induced by phenytoin intoxication in an adult patient with methylenetetrahydrofolate reductase deficiency

Author:

Arai Motomi,Osaka Hitoshi

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference13 articles.

1. Antiepileptic drugs as independent predictors of plasma total homocysteine levels;Apeland;Epilepsy Res,2001

2. Decreased hepatic 5,10-methylenetetrahydrofolate reductase activity in mice after chronic phenytoin treatment;Billings;Mol Pharmacol,1984

3. Folate-responsive homocystinuria and “schizophrenia.” A defect in methylation due to deficient 5,10-methylenetetrahydrofolate reductase activity;Freeman;N Engl J Med,1975

4. Severe and mild mutations in cis for the methylenetetrahydrofolate reductase (MTHFR) gene, and description of five novel mutations in MTHFR;Goyette;Am J Hum Genet,1996

5. Effect of betaine on S-adenosylmethionine levels in the cerebrospinal fluid in a patient with methylenetetrahydrofolate reductase deficiency and peripheral neuropathy;Kishi;J Inherit Metab Dis,1994

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