Melatonin rescues cardiac thioredoxin system during ischemia-reperfusion injury in acute hyperglycemic state by restoring Notch1/Hes1/Akt signaling in a membrane receptor-dependent manner

Author:

Yu Liming1,Fan Chongxi2,Li Zhi1,Zhang Jian1,Xue Xiaodong1,Xu Yinli1,Zhao Guolong3,Yang Yang45,Wang Huishan1

Affiliation:

1. Department of Cardiovascular Surgery; General Hospital of Shenyang Military Area Command; Shenyang Liaoning China

2. Department of Thoracic Surgery; Tangdu Hospital; The Fourth Military Medical University; Xi'an Shaanxi China

3. Department of Cardiovascular Surgery; Northwest Women's and Children's Hospital; Xi'an Shaanxi China

4. Department of Biomedical Engineering; The Fourth Military Medical University; Xi'an China

5. Department of Thoracic and Cardiovascular Surgery; Affiliated Drum Tower Hospital of Nanjing University Medical School; Nanjing Jiangsu China

Funder

National Natural Science Foundation of China

Key Scientific and Technological attack plan project of Liaoning Province

Publisher

Wiley

Subject

Endocrinology

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