Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study-Reference-Cited by-同舟云学术

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study

Published:2020-04-13 Issue:5 Volume:13 Page:972-984
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Jarmusch Alan K.¹,Vrbanac Alison²,Momper Jeremiah D.³,Ma Joseph D.³,Alhaja Maher³,Liyanage Marlon³,Knight Rob²⁴⁵,Dorrestein Pieter C.¹²⁴,Tsunoda Shirley M.³

Affiliation:

1. Skaggs School of Pharmacy and Pharmaceutical Sciences and Collaborative Mass Spectrometry Innovation Center University of California, San Diego La Jolla California USA

2. Department of Pediatrics University of California, San Diego La Jolla California USA

3. Skaggs School of Pharmacy and Pharmaceutical Sciences University of California, San Diego La Jolla California USA

4. Center for Microbiome Innovation University of California, San Diego La Jolla California USA

5. Department of Computer Science and Engineering University of California, San Diego La Jolla California USA

Funder

National Institutes of Health

Tsunoda

Center for Computational Mass Spectrometry

P.C.D.

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12785

Reference49 articles.

1. Pharmacomicrobiomics: The Holy Grail to Variability in Drug Response?

2. Intestinal anaerobic bacteria hydrolyse sorivudine, producing the high blood concentration of 5-(E)-(2-bromovinyl)uracil that increases the level and toxicity of 5-fluorouracil

3. A possible mechanism of eighteen patient deaths caused by interactions of sorivudine, a new antiviral drug, with oral 5‐fluorouracil prodrugs;Okuda H.;J. Pharmacol. Exp. Ther.,1998

4. Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

5. Gut microbiome modulates response to anti‐PD‐1 immunotherapy in melanoma patients;Gopalakrishnan V.;Science,2017

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