Hydrogen‐deuterium exchange mass spectrometry highlights conformational changes induced by factorXIactivation and binding of factorIXto factorXIa-Reference-Cited by-同舟云学术

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Hydrogen‐deuterium exchange mass spectrometry highlights conformational changes induced by factorXIactivation and binding of factorIXto factorXIa

Published:2019-10-07 Issue:12 Volume:17 Page:2047-2055
ISSN:1538-7933
Container-title:Journal of Thrombosis and Haemostasis
language:en
Short-container-title:J Thromb Haemost

Author:

Bar Barroeta Awital¹^ORCID,Galen Josse¹,Stroo Ingrid¹,Marquart J. Arnoud¹,Meijer Alexander B.¹²^ORCID,Meijers Joost C. M.¹³^ORCID

Affiliation:

1. Department of Molecular and Cellular Hemostasis Sanquin Research Amsterdam The Netherlands

2. Department of Pharmaceutics Utrecht Institute for Pharmaceutical Sciences (UIPS) Utrecht University Utrecht The Netherlands

3. Department of Experimental Vascular Medicine Amsterdam UMC University of Amsterdam Amsterdam The Netherlands

Funder

Landsteiner Foundation for Blood Transfusion Research

Ministerie van Volksgezondheid, Welzijn en Sport

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jth.14632

Reference23 articles.

1. Structure and function of factor XI

2. An update on factor XI structure and function

3. Thrombin-mediated activation of factor XI results in a thrombin-activatable fibrinolysis inhibitor-dependent inhibition of fibrinolysis.

4. Feedback activation of factor XI by thrombin in plasma results in additional formation of thrombin that protects fibrin clots from fibrinolysis;Borne PAK;Blood,1995

5. Rare bleeding disorders - bleeding assessment tools, laboratory aspects and phenotype and therapy of FXI deficiency

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1. The Light Chain Allosterically Enhances the Protease Activity of Murine Urokinase-Type Plasminogen Activator;Biochemistry;2024-05-23

2. Thrombin activation of the factor XI dimer is a multistaged process for each subunit;Journal of Thrombosis and Haemostasis;2024-05

3. Reversal of factor XI targeting anticoagulants: an in vitro evaluation;Journal of Thrombosis and Haemostasis;2024-01

4. The autoactivation of human single-chain urokinase-type plasminogen activator (uPA);Journal of Biological Chemistry;2023-10

5. Structures of factor XI and prekallikrein bound to domain 6 of high–molecular weight kininogen reveal alternate domain 6 conformations and exosites;Journal of Thrombosis and Haemostasis;2023-09

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