CBFA2T3-GLIS2-positive acute myeloid leukaemia. A peculiar paediatric entity

Author:

Masetti Riccardo1ORCID,Bertuccio Salvatore N.1ORCID,Pession Andrea1,Locatelli Franco2ORCID

Affiliation:

1. Department of Paediatrics; “Lalla Seràgnoli”, Haematology-Oncology Unit; University of Bologna; Bologna Italy

2. Department of Paediatric Haematology-Oncology and Cell and Gene Therapy; IRCCS Ospedale Pediatrico Bambino Gesù, Rome; Sapienza University of Rome; Rome Italy

Funder

Associazione Italiana per la Ricerca sul Cancro

Riccardo Masetti

Publisher

Wiley

Subject

Hematology

Reference44 articles.

1. Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding;Agyeman;Oncotarget,2014

2. Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis;Attanasio;Nature Genetics,2007

3. The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions;Bolouri;Nature Genetics,2018

4. Deletion of Mtg16, a target of t(16;21), alters hematopoietic progenitor cell proliferation and lineage allocation;Chyla;Molecular and Cellular Biology,2008

5. AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity;Creutzig;Leukemia,2005

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