COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type‐2 and PDE4 gene expression in sputum-Reference-Cited by-同舟云学术

COPD patients with chronic bronchitis and higher sputum eosinophil counts show increased type‐2 and PDE4 gene expression in sputum

Published:2020-12-09 Issue:2 Volume:25 Page:905-918
ISSN:1582-1838
Container-title:Journal of Cellular and Molecular Medicine
language:en
Short-container-title:J Cell Mol Med

Author:

Singh Dave¹,Bassi Michele²,Balzano Deborah²,Lucci Germano²,Emirova Aida²,Anna Nandeuil Marie²,Jellema Gera³,Afolabi Ebenezer K.³,Leaker Brian⁴,Kornmann Oliver⁵,Michael Beeh Kai⁶,Watz Henrik⁷,Govoni Mirco²^ORCID

Affiliation:

1. Medicines Evaluation Unit The University of Manchester Manchester University NHS Foundation Hospital Trust Manchester UK

2. Global Clinical Development Chiesi, Parma Italy

3. Almac Diagnostics Craigavon UK

4. The Heart Lung Centre London UK

5. IKF Pneumologie Frankfurt Clinical Research Centre Respiratory Diseases Frankfurt Germany

6. Insaf Respiratory Research Institute Wiesbaden Germany

7. Pulmonary Research Institute at Lung Clinic Grosshansdorf Airway Research Center North (ARCN) Member of the German Center for Lung Research (DZL) Grosshansdorf Germany

Funder

Chiesi Farmaceutici

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jcmm.16146

Reference56 articles.

1. Sputum Eosinophilia Predicts Benefit from Prednisone in Smokers with Chronic Obstructive Bronchitis

2. Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids

3. Blood Eosinophil Counts in Clinical Trials for Chronic Obstructive Pulmonary Disease