Genome-wide association study of chemotherapeutic agent-induced severe neutropenia/leucopenia for patients in Biobank Japan

Author:

Low Siew-Kee,Chung Suyoun,Takahashi Atsushi1,Zembutsu Hitoshi2,Mushiroda Taisei3,Kubo Michiaki4,Nakamura Yusuke

Affiliation:

1. Laboratory for Statistical Analysis, Center for Genomic Medicine; RIKEN; Yokohama; Japan

2. Laboratory of Molecular Medicine, Human Genome Center; Institute of Medical Science, The University of Tokyo; Tokyo; Japan

3. Laboratory for Pharmacogenetics, Center for Genomic Medicine; RIKEN; Yokohama; Japan

4. Laboratory for Genotyping Development; Center for Genomic Medicine, RIKEN; Yokohama; Japan

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Reference32 articles.

1. Cancer pharmacogenomics: strategies and challenges;Wheeler;Nat Rev Genet,2013

2. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus;Relling;J Natl Cancer Inst,1999

3. Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity;Weinshilboum;Am J Hum Genet,1980

4. CPIC: clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network;Relling;Clin Pharmacol Ther,2011

5. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan;Innocenti;J Clin Oncol,2004

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