Affiliation:
1. Nervous System Stem Cells Research Center Semnan University of Medical Sciences Semnan Iran
2. Department of Tissue Engineering and Applied Cell Sciences School of Medicine Semnan University of Medical Sciences Semnan Iran
3. College of Engineering University of Tehran Tehran Iran
4. Department of Tissue Engineering and Applied Cell Sciences School of Advanced Technologies in Medicine Iran University of Medical Sciences Tehran Iran
5. Student Research Committee School of Medicine Shahroud University of Medical Sciences Shahroud Iran
Abstract
AbstractBackgroundTissue engineering and regenerative medicine (TERM) aim to repair or replace damaged or lost tissues or organs due to accidents, diseases, or aging, by applying different sciences. For this purpose, an essential part of TERM is the designing, manufacturing, and evaluating of scaffolds, cells, tissues, and organs. Artificial intelligence (AI) or the intelligence of machines or software can be effective in all areas where computers play a role.MethodsThe “artificial intelligence,” “machine learning,” “tissue engineering,” “clinical evaluation,” and “scaffold” keywords used for searching in various databases and articles published from 2000 to 2024 were evaluated.ResultsThe combination of tissue engineering and AI has created a new generation of technological advancement in the biomedical industry. Experience in TERM has been refined using advanced design and manufacturing techniques. Advances in AI, particularly deep learning, offer an opportunity to improve scientific understanding and clinical outcomes in TERM.ConclusionThe findings of this research show the high potential of AI, machine learning, and robots in the selection, design, and fabrication of scaffolds, cells, tissues, or organs, and their analysis, characterization, and evaluation after their implantation. AI can be a tool to accelerate the introduction of tissue engineering products to the bedside.Highlights
The capabilities of artificial intelligence (AI) can be used in different ways in all the different stages of TERM and not only solve the existing limitations, but also accelerate the processes, increase efficiency and precision, reduce costs, and complications after transplantation.
ML predicts which technologies have the most efficient and easiest path to enter the market and clinic.
The use of AI along with these imaging techniques can lead to the improvement of diagnostic information, the reduction of operator errors when reading images, and the improvement of image analysis (such as classification, localization, regression, and segmentation).