The Immunosuppressive Effect of CTLA4 Immunoglobulin Is Dependent on Regulatory T Cells at Low But Not High Doses-Reference-Cited by-同舟云学术

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The Immunosuppressive Effect of CTLA4 Immunoglobulin Is Dependent on Regulatory T Cells at Low But Not High Doses

Published:2016-07-05 Issue:12 Volume:16 Page:3404-3415
ISSN:1600-6135
Container-title:American Journal of Transplantation
language:en
Short-container-title:Am J Transplant

Author:

Schwarz C.¹,Unger L.¹,Mahr B.¹,Aumayr K.²,Regele H.²,Farkas A. M.¹,Hock K.¹,Pilat N.¹^ORCID,Wekerle T.¹

Affiliation:

1. Section of Transplantation Immunology; Department of Surgery; Medical University of Vienna; Vienna Austria

2. Clinical Institute of Pathology; Medical University of Vienna; Vienna Austria

Funder

Bristol-Myers Squibb Pharmaceuticals

Medical Scientific Fund of the Mayor of the City of Vienna

Hochschuljubiläumsstiftung of Vienna

Publisher

Wiley

Subject

Pharmacology (medical),Transplantation,Immunology and Allergy

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/ajt.13872/fullpdf

Reference57 articles.

1. Belatacept: From rational design to clinical application;Wekerle;Transpl Int,2012

2. Understanding the CD28/CTLA-4 (CD152) pathway and its implications for costimulatory blockade;Gardner;Am J Transplant,2014

3. A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study);Vincenti;Am J Transplant,2010

4. Does belatacept improve outcomes for kidney transplant recipients? A systematic review;Talawila;Transpl Int,2015

5. Homeostatic control of regulatory T cell diversity;Liston;Nat Rev Immunol,2014

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1. Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer;European Journal of Medical Research;2024-07-02

2. IL-6 inhibition prevents costimulation blockade-resistant allograft rejection in T cell-depleted recipients by promoting intragraft immune regulation in mice;Nature Communications;2024-06-03

3. Protein Phosphatase 2A Activation Promotes Heart Transplant Acceptance in Mice;Transplantation;2023-10-17

4. Monitoring regulatory T cells as a prognostic marker in lung transplantation;Frontiers in Immunology;2023-09-25

5. Tregs in transplantation tolerance: role and therapeutic potential;Frontiers in Transplantation;2023-08-30

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