Affiliation:
1. VIROS – Vienna Institute for Research in Ocular Surgery Karl Landsteiner Institute Hanusch Hospital Vienna Austria
2. Department of Clinical Pharmacology Medical University of Vienna Vienna Austria
3. Department of Ophthalmology and Optometry Kepler University Hospital GmbH Linz Austria
4. Johannes Kepler University Linz Medical Faculty Linz Austria
Abstract
AbstractPurposeTo evaluate the effect of vectored thermal pulsation therapy (VTPT) on the repeatability of biometry readings of two different optical biometers in patients with meibomian gland dysfunction (MGD).MethodsPatients affected by MGD were included in this prospective, randomized, controlled, investigator‐masked study. One eye was randomized to VTPT (LipiFlow®, Johnson & Johnson), and the contralateral eye served as a control. Three visits were scheduled at baseline, 2 weeks and 3 months after the treatment. The main outcome parameter of the study was the repeatability of three calculations of emmetropic intraocular lens power (EIOLP) at the 3 months visit as compared to baseline using an optical biometer (IOLMaster® 700, Carl Zeiss Meditec AG). Repeatability of different keratometry values obtained by the optical biometer and a Placido‐disc topographer (MS‐39®, CSO) served as secondary outcome parameters.ResultsTwenty‐nine patients were included in the final analysis. While tear film parameters improved in the study eyes, there were no significant differences regarding the repeatability of three EIOLP measurements between baseline and 3‐months‐visit in both eyes (p > 0.05) and keratometry measurements in both the optical biometer and the Placido‐disc topographer. Remarkably, throughout all study visits, there were some outliers regarding the repeatability of measurements.ConclusionWhile both devices showed high repeatability regarding EIOLP and keratometry, future studies are needed to detect high‐risk patients for poor repeatability.
Subject
Ophthalmology,General Medicine