Improving standard practices in studies using results from basic human semen examination

Author:

Björndahl Lars1ORCID,Esteves Sandro C.234ORCID,Ferlin Alberto5ORCID,Jørgensen Niels67ORCID,O'Flaherty Cristian891011ORCID

Affiliation:

1. ANOVA Karolinska University Hospital and Karolinska Institutet Stockholm Sweden

2. ANDROFERT Andrology and Human Reproduction Clinic Campinas São Paulo Brazil

3. Department of Surgery (Urology Division) University of Campinas (UNICAMP) Campinas São Paulo Brazil

4. Faculty of Health Aarhus University Aarhus Denmark

5. Department of Medicine, Unit of Andrology and Repoductive Medicine University of Padova Padova Italy

6. Department of Growth and Reproduction Copenhagen University Hospital ‐ Rigshospitalet Copenhagen Denmark

7. International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet Copenhagen University Hospital ‐ Rigshospitalet Copenhagen Denmark

8. Surgery (Urology Division) Montréal Québec Canada

9. Pharmacology and Therapeutics Montréal Québec Canada

10. Anatomy and Cell Biology, Faculty of Medicine and Health Sciences McGill University Montréal Québec Canada

11. The Research Institute McGill University Health Centre Montréal Québec Canada

Abstract

AbstractThe purpose of this article is to provide an explanation of the background behind a checklist that declares the laboratory methods used in a scientific study. It focuses primarily on implementing laboratory procedures to yield reliable results in basic semen examinations. While the World Health Organization (WHO) and international standards provide recommendations for basic semen examination, manuscripts submitted to Andrology frequently lack transparency regarding the specific techniques used. In addition, the terminology used for semen examination results often fails to provide a clear definition of the groups under study. Furthermore, the WHO's reference limits are often misinterpreted as strict boundaries between fertility and infertility. It is important to note that valid clinical andrological diagnoses and treatments cannot rely solely on semen examination results; they require proper laboratory procedures as a foundation for diagnosing and treating male patients. Therefore, scientific journals should promote the adoption of robust laboratory practices and an accurate definition of patient groups. A checklist can facilitate the design of high‐quality studies and the creation of informative publications. Further, it can help journals assess submitted manuscripts and improve the overall quality of their publications.

Publisher

Wiley

Subject

Urology,Endocrinology,Reproductive Medicine,Endocrinology, Diabetes and Metabolism

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