Artificial intelligence as a prediction tool for orthognathic surgery assessment

Author:

de Oliveira Pedro Henrique José1ORCID,Li Tengfei2ORCID,Li Haoyue3ORCID,Gonçalves João Roberto1ORCID,Santos‐Pinto Ary1ORCID,Gandini Junior Luiz Gonzaga1ORCID,Cevidanes Lucia Soares4ORCID,Toyama Claudia5,Feltrin Guilherme Paladini6,Campanha Antonio Augusto7,de Oliveira Junior Melchiades Alves7,Bianchi Jonas18ORCID

Affiliation:

1. Department of Morphology, Genetics, Orthodontics and Pediatric Dentistry, School of Dentistry São Paulo State University (Unesp) Araraquara São Paulo Brazil

2. Department of Radiology and Biomedical Research Imaging Center University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

3. Department of Biostatistics University of North Carolina at Chapel Hill Chapel Hill North Carolina USA

4. Department of Orthodontics and Pediatric Dentistry University of Michigan Ann Arbor Michigan USA

5. Private practice São Paulo São Paulo Brazil

6. Private practice Maringá São Paulo Brazil

7. Private practice Campinas São Paulo Brazil

8. Department of Orthodontics University of the Pacific, Arthur A. Dugoni School of Dentistry San Francisco California USA

Abstract

AbstractIntroductionAn ideal orthodontic treatment involves qualitative and quantitative measurements of dental and skeletal components to evaluate patients' discrepancies, such as facial, occlusal, and functional characteristics. Deciding between orthodontics and orthognathic surgery remains challenging, especially in borderline patients. Advances in technology are aiding clinical decisions in orthodontics. The increasing availability of data and the era of big data enable the use of artificial intelligence to guide clinicians' diagnoses. This study aims to test the capacity of different machine learning (ML) models to predict whether orthognathic surgery or orthodontics treatment is required, using soft and hard tissue cephalometric values.MethodsA total of 920 lateral radiographs from patients previously treated with either conventional orthodontics or in combination with orthognathic surgery were used, comprising n = 558 Class II and n = 362 Class III patients, respectively. Thirty‐two measures were obtained from each cephalogram at the initial appointment. The subjects were randomly divided into training (n = 552), validation (n = 183), and test (n = 185) datasets, both as an entire sample and divided into Class II and Class III sub‐groups. The extracted data were evaluated using 10 machine learning models and by a four‐expert panel consisting of orthodontists (n = 2) and surgeons (n = 2).ResultsThe combined prediction of 10 models showed top‐ranked performance in the testing dataset for accuracy, F1‐score, and AUC (entire sample: 0.707, 0.706, 0.791; Class II: 0.759, 0.758, 0.824; Class III: 0.822, 0.807, 0.89).ConclusionsThe proposed combined 10 ML approach model accurately predicted the need for orthognathic surgery, showing better performance in Class III patients.

Funder

National Institute of Dental and Craniofacial Research

Publisher

Wiley

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