Enhanced microglial pro‐inflammatory response to lipopolysaccharide correlates with brain infiltration and blood–brain barrier dysregulation in a mouse model of telomere shortening-Reference-Cited by-同舟云学术

Enhanced microglial pro‐inflammatory response to lipopolysaccharide correlates with brain infiltration and blood–brain barrier dysregulation in a mouse model of telomere shortening

Published:2015-08-03 Issue:6 Volume:14 Page:1003-1013
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Raj Divya D. A.¹,Moser Jill²³,Pol Susanne M. A.⁴,Os Ronald P.⁵,Holtman Inge R.¹,Brouwer Nieske¹,Oeseburg Hisko⁶,Schaafsma Wandert¹,Wesseling Evelyn M.¹,Dunnen Wilfred³,Biber Knut P. H.¹⁷,Vries Helga E.⁴,Eggen Bart J. L.¹,Boddeke Hendrikus W. G. M.¹

Affiliation:

1. Section Medical Physiology Department of Neuroscience University of Groningen University Medical Center Groningen Groningen 9713 AVThe Netherlands

2. Department of Critical Care University of Groningen University Medical Center Groningen Groningen 9713 AV The Netherlands

3. Department of Pathology and Medical Biology University of Groningen University Medical Center Groningen Groningen 9713 AVThe Netherlands

4. Blood‐Brain Barrier Research Group Department of Molecular Cell Biology and Immunology Neuroscience Campus Amsterdam VU University Medical Centre PO Box 70571007 MBAmsterdam The Netherlands

5. Department of Cell Biology European Research Institute on the Biology of Aging University of Groningen University Medical Center Groningen 9713 AVThe Netherlands

6. Department of Cardiology University Medical Center Groningen Groningen 9713 AVThe Netherlands

7. Department of Psychiatry and Psychotherapy University Medical Center Freiburg 79104Germany

Funder

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12370

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1. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life