Multi‐disciplinary diabetic limb salvage programme in octogenarians with diabetic foot ulcers is not futile: An observational study with historical controls

Author:

Ge Lixia1ORCID,Zhao Jiashen2,Tan Matthew3,Tan Elaine4,Liew Huiling5ORCID,Yong Enming6,Hoe Jeremy7,Shi Claris8,Chan Dexter Yak Seng9ORCID,Ang Gary Yee1,Molina Joseph Antonio1,Sun Yan1,Hoi Wai Han10,Chandraskear Sadhana11,Lo Zhiwen Joseph1112ORCID

Affiliation:

1. Health Services and Outcomes Research National Healthcare Group Singapore Singapore

2. Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

3. Section of Vascular Surgery, Department of Surgery and Cancer Imperial College London London UK

4. Medical Department National Healthcare Group Polyclinics Singapore Singapore

5. Department of Endocrinology Tan Tock Seng Hospital Singapore Singapore

6. Department of General Surgery Tan Tock Seng Hospital Singapore Singapore

7. Department of Endocrinology Khoo Teck Puat Hospital Singapore Singapore

8. Department of Orthopaedics Surgery Khoo Teck Puat Hospital Singapore Singapore

9. Vascular Surgery Service, Department of General Surgery Khoo Teck Puat Hospital Singapore Singapore

10. Department of Endocrinology Woodlands Health Singapore Singapore

11. Vascular Surgery Service, Department of Surgery Woodlands Health Singapore Singapore

12. Lee Kong Chian School of Medicine Nanyang Technological University Singapore Singapore

Abstract

AbstractThis study evaluated the effectiveness of a multi‐disciplinary diabetic limb salvage programme in improving clinical outcomes and optimising healthcare utilisation in 406 patients aged ≥80 years with diabetic foot ulcers (DFUs), compared to 2392 younger patients enrolled from June 2020 to June 2021 and against 1716 historical controls using one‐to‐one propensity score matching. Results showed that elderly programme patients had lower odds of amputation‐free survival (odds ratio: 0.64, 95% CI: 0.47, 0.88) and shorter cumulative length of stay (LOS) compared to younger programme patients (incidence rate ratio: 0.45, 95% CI: 0.29, 0.69). Compared to the matched controls, participating in the programme was associated with 5% higher probability of minor lower extremity amputation, reduced inpatient admissions and emergency visits, shorter LOS but increased specialist and primary care visits (all p‐values <0.05). The findings suggest that the programme yielded favourable impacts on the clinical outcomes of patients aged≥80 years with DFUs. Further research is needed to develop specific interventions tailoring to the needs of the elderly population and to determine their effectiveness on patient outcomes while accounting for potential confounding factors.

Funder

Agency for Science, Technology and Research

National Healthcare Group

National Medical Research Council

Publisher

Wiley

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