Evaluation of the effect of fluconazole on the pharmacokinetics of cyclosporin A in healthy dogs after a single dose and at steady-state

Author:

Pieper J. B.1,Dirikolu L.2,Campbell K. L.1,Li Z.3,Mitchell M. A.1

Affiliation:

1. Department of Veterinary Clinical Medicine; University of Illinois; Urbana IL USA

2. Department of Comparative Biomedical Sciences; Louisiana State University; Baton Rouge LA USA

3. Metabolomics Center of Roy J. Carver Biotechnology Center; University of Illinois; Urbana IL USA

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference32 articles.

1. Effect of grapefruit juice on the pharmacokinetics of cyclosporine in dogs;Amatori;Veterinary Record,2004

2. Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver;Aoyama;The Journal of Biological Chemistry,1989

3. Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporine by human liver microsomes;Back;British Journal of Clinical Pharmacology,1991

4. Alterations in cyclosporin a pharmacokinetics and metabolism during treatment with St. John's Wort in renal transplant patients;Bauer;British Journal of Clinical Pharmacology,2003

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