An integrated PK‐PD model for cortisol and the 17‐hydroxyprogesterone and androstenedione biomarkers in children with congenital adrenal hyperplasia

Author:

Al‐Kofahi Mahmoud1ORCID,Ahmed Mariam A.12ORCID,Jaber Mutaz M.1ORCID,Tran Thang N.1,Willis Brian A.3ORCID,Zimmerman Cheryl L.1,Gonzalez‐Bolanos Maria T.4,Brundage Richard C.1ORCID,Sarafoglou Kyriakie14ORCID

Affiliation:

1. Department of Experimental and Clinical Pharmacology University of Minnesota Minneapolis MN USA

2. College of Pharmacy Helwan University Egypt

3. Lilly Research Laboratories Eli Lilly and Company Indianapolis IN USA

4. Department of Pediatrics University of Minnesota Masonic Children's Hospital Minneapolis MN USA

Funder

Food and Drug Administration

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference54 articles.

1. Twenty-four Hour Pattern of the Episodic Secretion of Cortisol in Normal Subjects

2. Free Cortisol Levels after Awakening: A Reliable Biological Marker for the Assessment of Adrenocortical Activity

3. Amplitude modulation of a burstlike mode of cortisol secretion subserves the circadian glucocorticoid rhythm;Veldhuis JD;Am J Physiol,1989

4. Synchronous ultradian rhythms in adrenocortical secretion detected by microdialysis in awake rats;Jasper MS;Am J Physiol,1991

5. Estimation of daily cortisol production and clearance rates in normal pubertal males by deconvolution analysis;Kerrigan JR;J Clin Endocrinol Metab,1993

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