Evaluation of toxicities from combined metronomic and maximal-tolerated dose chemotherapy in dogs with osteosarcoma

Author:

Bracha S.1,Walshaw R.2,Danton T.3,Holland S.4,Ruaux C.1,Obradovich J.5

Affiliation:

1. Department of Clinical Sciences, College of Veterinary Medicine; Oregon State University; Corvallis OR 97331 USA

2. Surgical Oncology; Dearborn MI USA

3. College of Veterinary Medicine; Michigan State University; East Lansing MI 48824 USA

4. Sanford Brown College; Dearborn MI 48126 USA

5. Animal Cancer and Imaging Center; Canton MI 48187 USA

Publisher

Wiley

Subject

Small Animals

Reference30 articles.

1. Carboplatin and doxorubicin combination chemotherapy for the treatment of appendicular osteosarcoma in the dog;Bailey;Journal of Veterinary Internal Medicine,2003

2. Amputation and carboplatin for treatment of dogs with osteosarcoma: 48 cases (1991 to 1993);Bergman;Journal of Veterinary Internal Medicine,1996

3. Maximum tolerable dose and low-dose metronomic chemotherapy have opposite effects on the mobilization and viability of circulating endothelial progenitor cells;Bertolini;Cancer Research,2330

4. Carboplatin and piroxicam therapy in 31 dogs with transitional cell carcinoma of the urinary bladder;Boria;Veterinary and Comparative Oncology,2005

5. Low-dose cyclophosphamide selectively decreases regulatory t cells and inhibits angiogenesis in dogs with soft tissue sarcoma;Burton;Journal of Veterinary Internal Medicine,2011

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