Effect of metformin on germ cell-specific apoptosis, oxidative stress and epididymal sperm quality after testicular torsion/detorsion in rats

Author:

Ghasemnejad-Berenji M.123,Ghazi-Khansari M.1,Yazdani I.12,Nobakht M.4,Abdollahi A.5,Ghasemnejad-Berenji H.6,Mohajer Ansari J.4,Pashapour S.7,Dehpour A. R.12ORCID

Affiliation:

1. Department of Pharmacology; School of Medicine; Tehran University of Medical Sciences; Tehran Iran

2. Experimental Medicine Research Center; Tehran University of Medical Sciences; Tehran Iran

3. Department of Pharmacology; Faculty of Pharmacy; Urmia University of Medical Sciences; Urmia Iran

4. Department of Anatomy; School of Medicine; Iran University of Medical Sciences; Tehran Iran

5. Department of Pathology; Cancer Institute; Tehran University of Medical Sciences; Tehran Iran

6. Department of Anatomy and Reproductive Biology; School of Medicine; Shahid Beheshti University of Medical Sciences; Tehran Iran

7. Department of Pathology; Urmia University of Medical Science; Urmia Iran

Funder

Tehran University of Medical Sciences and Health Services

Publisher

Wiley

Subject

Urology,Endocrinology,General Medicine

Reference60 articles.

1. Modulation of the oxidative stress by metformin in the cerebrum of rats exposed to global cerebral ischemia and ischemia/reperfusion;Abd-Elsameea;European Review for Medical and Pharmacological Sciences,2014

2. [13] Catalase in vitro;Aebi;Methods in Enzymology,1984

3. Role of oxidants in male infertility: Rationale, significance, and treatment;Agarwal;Urologic Clinics of North America,2002

4. Gradual detorsion of torsioned rat testis attenuates ischemia reperfusion injury;Akçora;Journal of Pediatric Surgery,2008

5. Protective effect of metformin on testicular ischemia/reperfusion injury in rats;Asghari;Acta Cirurgica Brasileira,2016

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