A pilot, open-label study of the effectiveness and tolerability of low-dose ZX008 (fenfluramine HCl) in Lennox-Gastaut syndrome

Author:

Lagae Lieven1,Schoonjans An-Sofie2,Gammaitoni Arnold R.3,Galer Bradley S.3,Ceulemans Berten2

Affiliation:

1. Department of Development and Regeneration; Division of Pediatric Neurology; University of Leuven; Leuven Belgium

2. Division of Pediatric Neurology; Antwerp University Hospital; University of Antwerp; Edegem Belgium

3. Zogenix; Emeryville California

Funder

Zogenix

Publisher

Wiley

Subject

Clinical Neurology,Neurology

Reference28 articles.

1. Lennox-Gastaut syndrome: a consensus approach on diagnosis, assessment, management, and trial methodology;Arzimanoglou;Lancet Neurol,2009

2. Expert opinion on the management of Lennox-Gastaut syndrome: treatment algorithms and practical considerations;Cross;Front Neurol,2017

3. Treatment of Lennox-Gastaut syndrome;Hancock;Cochrane Database Syst Rev,2013

4. Early diagnosis and treatment of Lennox-Gastaut syndrome;Resnick;J Child Neurol,2017

5. National Institute for Health and Care Excellence Epilepsies: diagnosis and management 2018 https://www.nice.org.uk/guidance/cg137

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