Lack of Fc Gamma Receptor IIIA Promotes Rather than Suppresses Humoral and Cellular Immune Responses after Mucosal or Parenteral Immunization with Antigen and Adjuvants

Author:

Sun J.-B.1,Holmgren J.1,Cragg M. S.2,Xiang Z.13

Affiliation:

1. Department of Microbiology and Immunology and University of Gothenburg Vaccine Research Institute (GUVAX); Institute of Biomedicine; Sahlgrenska Academy at University of Gothenburg; Göteborg Sweden

2. Antibody and Vaccine Group; Cancer Sciences Unit; Faculty of Medicine; Southampton General Hospital; University of Southampton; Southampton Hampshire UK

3. Department of Health Technology and Informatics; Faculty of Health and Social Sciences; The Hong Kong Polytechnic University; Hong Kong China

Funder

Vetenskapsrådet

EU Aditec Program

Swedish Strategic Research Foundation

Publisher

Wiley

Subject

Immunology,General Medicine

Reference35 articles.

1. Fc receptors as adaptive immunoreceptors;Daeron;Curr Top Microbiol Immunol,2014

2. The mast cell IgG receptors and their roles in tissue inflammation;Malbec;Immunol Rev,2007

3. Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice;Hazenbos;Immunity,1996

4. Mouse and human neutrophils induce anaphylaxis;Jonsson;J Clin Invest,2011

5. Arthritis critically dependent on innate immune system players;Ji;Immunity,2002

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