Design, synthesis, and biological evaluation of thieno[3,2‐d]pyrimidine derivatives as potential simplified phosphatidylinositol 3‐kinase alpha inhibitors-Reference-Cited by-同舟云学术

Design, synthesis, and biological evaluation of thieno[3,2‐d]pyrimidine derivatives as potential simplified phosphatidylinositol 3‐kinase alpha inhibitors

Published:2019-10-14 Issue:6 Volume:94 Page:2013-2022
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Yang Xiuyan¹,Deng Meng¹,Zhang Xi²,Wang Yi²,Song Kun¹,Cong Ruan¹,Meng Linghua²,Zhang Jian¹³^ORCID

Affiliation:

1. Department of PathophysiologyKey Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of EducationShanghai Jiao Tong University School of Medicine Shanghai China

2. Division of Anti‐tumor PharmacologyShanghai Institute of Materia MedicaChinese Academy of Sciences Shanghai China

3. Basic Clinical Research CenterRenji HospitalShanghai Jiao Tong University School of Medicine Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.13425

Reference34 articles.

1. The Phosphoinositide 3-Kinase Pathway in Human Cancer: Genetic Alterations and Therapeutic Implications