Histamine H4 receptor knockout mice display reduced inflammation in a chronic model of atopic dermatitis

Author:

Rossbach K.1,Schaper K.2,Kloth Ch.3,Gutzmer R.2,Werfel T.2,Kietzmann M.1,Bäumer W.14

Affiliation:

1. Institute for Pharmacology, Toxicology and Pharmacy; University of Veterinary Medicine; Hannover Germany

2. Division of Immunodermatology and Allergy Research; Department of Dermatology and Allergy; Hannover Medical School; Hannover Germany

3. Institute for Pharmacology; Hannover Medical School; Hannover Germany

4. Department of Molecular Biomedical Sciences; College of Veterinary Medicine; NC State University; Raleigh NC USA

Funder

Deutsche Forschungsgemeinschaft

Janssen Research and Development

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference36 articles.

1. Atopic dermatitis and the atopic march;Spergel;J Allergy Clin Immunol,2003

2. Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report;Akdis;J Allergy Clin Immunol,2006

3. The histamine H4 receptor as a new therapeutic target for inflammation;Esch;Trends Pharmacol Sci,2005

4. The role of histamine H4 receptor in immune and inflammatory disorders;Zampeli;Br J Pharmacol,2009

5. Histamine as an immunomodulator;Baumer;J Dtsch Dermatol Ges,2010

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