Cytochrome P450 3A and P-glycoprotein drug-drug interactions with voclosporin

Author:

Ling Spencer Y.1ORCID,Huizinga Robert B.1ORCID,Mayo Patrick R.1,Larouche Richard2,Freitag Derrick G.1,Aspeslet Launa J.1,Foster Robert T.1

Affiliation:

1. Isotechnika Pharma Inc.; Edmonton Alberta Canada

2. Inventiv Health Clinical; Montréal Québec Canada

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference26 articles.

1. Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin);Kuglstatter;Acta Crystallogr D Biol Crystallogr,2011

2. In vivo evaluation of the novel calcineurin inhibitor ISATX247 in non-human primates;Stalder;J Heart Lung Transplant,2003

3. Draft Guidance for Industry. Drug Interaction Studies - Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) 2006

4. Draft Guidance for Industry. Drug Interaction Studies - Study Design, Data Analysis, Implications for Dosing, and Labeling Recommendations U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) 2012

5. Development and validation of a LC/MS/MS method for quantifying the next generation calcineurin inhibitor, voclosporin, in human whole blood;Handy;J Chromatogr B Analyt Technol Biomed Life Sci,2008

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