Affiliation:
1. Cardiac Surgery Unit Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe‐J) University of Bari Medical School Bari Italy
2. Intensive Care Unit Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe‐J) University of Bari Medical School Bari Italy
Abstract
AbstractA 59‐year‐old woman, with dilated ischemic cardiomyopathy, was urgently admitted to our Intensive Care Unit for cardiogenic shock. ECMO VA was implanted and placed on the national emergency waitlist for transplantation. A potential donation was identified ten days later. The donor was a 58‐year‐old woman, with no cardiovascular risk factors, had died of a rupture of a cerebral aneurysm with left ventricle dysfunction due to Takotsubo syndrome. Brain injuries such as hemorrhage, trauma and stroke have been extensively documented in literature to cause a surge in stress hormones, such as catecholamines. Such a surge can have a direct effect on the heart, resulting in a transient myocardial dysfunction commonly referred to as “Takotsubo cardiomyopathy” or “broken heart syndrome”.Many studies have shown that hearts that are dysfunctional at the start of transplant screening, with normal contractile function at the time of organ retrieval, have similar outcomes to hearts that do not have dysfunction. In our case, the transplanted heart, at the time of sampling, still had moderate dysfunction (EF 40%) which completely disappeared after the transplant.