Different apoptotic effects of [Pt(O,O′-acac)(γ-acac)(DMS)] and cisplatin on normal and cancerous human epithelial breast cells in primary culture

Author:

Vetrugno Carla1,Muscella Antonella2,Fanizzi Francesco Paolo3,Cossa Luca Giulio1,Migoni Danilo3,De Pascali Sandra Angelica3,Marsigliante Santo1

Affiliation:

1. Cell Physiology Lab; Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.); Universita' del Salento; Lecce Italy

2. Cell Pathology Lab; Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.); Universita' del Salento; Lecce Italy

3. General and Inorganic Chemistry Lab; Dipartimento di Scienze e Tecnologie Biologiche e Ambientali (Di.S.Te.B.A.); Universita' del Salento; Lecce Italy

Funder

Italian Ministry of Research and University PRIN2009

Publisher

Wiley

Subject

Pharmacology

Reference54 articles.

1. The Concise Guide to PHARMACOLOGY 2013/14: Enzymes;Alexander;British J Pharm,2013

2. BCL-2 antisense and cisplatin combination treatment of MCF-7 breast cancer cells with or without functional p53;Basma;J Biomed Sci,2005

3. Caspase-3 is essential for procaspase-9 processing and cisplatin-induced apoptosis of MCF-7 breast cancer cells;Blanc;Cancer Res,2000

4. The developmental neurotoxicity study of platinum compounds. Effects of cisplatin versus a novel Pt(II) complex on rat cerebellum;Cerri;Neurotoxicol Teratol,2011

5. Metal complexes in medicine with a focus on enzyme inhibition;Che;Curr Opin Chem Biol,2010

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