Reversal of apixaban anticoagulation by four-factor prothrombin complex concentrates in healthy subjects: a randomized three-period crossover study
Author:
Affiliation:
1. Bristol-Myers Squibb; Princeton NJ USA
Funder
Bristol-Myers Squibb
Pfizer
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/jth.13815/fullpdf
Reference46 articles.
1. Bristol-Myers Squibb Coumadin prescribing information http://packageinserts.bms.com/pi/pi_coumadin.pdf
2. Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial;Goldstein;Lancet,2015
3. Boehringer Ingelheim Pradaxa (dabigatran) PI http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206316lbl.pdf
4. Idarucizumab for dabigatran reversal;Pollack;N Engl J Med,2015
5. Reversing the effect of oral anticoagulant drugs: established and newer options;Ansell;Am J Cardiovasc Drugs,2016
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