Forssman and the staphylococcal hemolysins

Author:

Ingmer Hanne1ORCID,Leisner Jørgen J.1,Fulaz Stephanie1

Affiliation:

1. Department of Veterinary and Animal Science University of Copenhagen Copenhagen Denmark

Abstract

Forssman was a Swedish pathologist and microbiologist who, in the 1920s and 1930s conducted a long series of experiments that led to unique insights into surface antigens of blood cells, as well as added to the discrimination of toxins produced by staphylococci that lyse red blood cells. This review takes offset in the studies published by Forssman in APMIS addressing the hemolytic properties of staphylococcal toxins displayed against erythrocytes of animal and human origin. In light of current knowledge, we will discuss the insights we now have and how they may pave the way for curing infections with pathogenic staphylococci, including Staphylococcus aureus.

Funder

Norges Forskningsråd

LEO Fondet

Novo Nordisk Fonden

Publisher

Wiley

Reference116 articles.

1. AhleniusE.Finansiering av medicinsk forskning genom stiftelsen Therese och Johan Anderssons minne 1931–1964 in Uppsala Universitet Ekonomisk historia B.2016.

2. Die Herstellung hochwertiger spezifischer Schafhämonysine ohne Verwendung von Schafblut. Ein Beitrag zur Lehre von heterologer Antikörpebildung;Forssman J;Biochem Z,1911

3. Glycophylogenetic Aspects

4. Some experiments on the origin of Normal F‐Haemolysin in rabbits and on the occurrence of F‐antigen in plants;Forssman J;Acta Pathol Microbiol Scand,1945

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