Darexaban has high sensitivity in the prothrombin time clotting test-Reference-Cited by-同舟云学术

Darexaban has high sensitivity in the prothrombin time clotting test

Published:2012-03-30 Issue:4 Volume:10 Page:703-705
ISSN:1538-7933
Container-title:Journal of Thrombosis and Haemostasis
language:en
Short-container-title:

Author:

FUNATSU T.,IWATSUKI Y.,KAKU S.

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1538-7836.2012.04655.x/fullpdf

Reference8 articles.

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3. YM150, an oral direct inhibitor of factor Xa, demonstrated a predictable and dose-proportional pharmacokinetic/pharmacodynamic profile after single and multiple dosing: results from three studies;Groenendaal;Blood,2010

4. Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor;Kubitza;Clin Pharmacol Ther,2005

5. Apixaban metabolism and pharmacokinetics after oral administration to humans;Raghavan;Drug Metab Dispos,2009

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1. Clinical pharmacokinetics, pharmacodynamics, safety and tolerability of darexaban, an oral direct factor Xa inhibitor, in healthy Caucasian and Japanese subjects;Biopharmaceutics & Drug Disposition;2013-09-20

2. Clinical Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Darexaban, an Oral Direct Factor Xa Inhibitor, in Healthy Elderly Japanese Subjects;Clinical Pharmacology in Drug Development;2013-08-16

3. Darexaban: Anticoagulant effects in mice and human plasma in vitro, antithrombotic effects in thrombosis and bleeding models in mice and effects of anti-inhibitor coagulant complex and recombinant factor VIIa;Thrombosis Research;2013-05

4. Plasma factor Xa inhibition can predict antithrombotic effects of oral direct factor Xa inhibitors in rabbit atherothrombosis models;Thrombosis and Haemostasis;2012