Apigenin-induced nitric oxide production involves calcium-activated potassium channels and is responsible for antiangiogenic effects
Author:
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1538-7836.2007.02615.x/fullpdf
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1. Flavonoids inhibit melanoma lung metastasis by impairing tumor cells endothelium interactions
2. Flavonoids inhibit VEGF/bFGF-induced angiogenesis in vitro by inhibiting the matrix-degrading proteases
3. Apigenin suppresses the expression of VEGF, an important factor for angiogenesis, in endothelial cells via degradation of HIF-1α protein
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