Generation of a novel factor IX with augmented clotting activitiesin vitroandin vivo
Author:
Publisher
Wiley
Subject
Hematology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1538-7836.2010.03913.x/fullpdf
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3. Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa;Chang;J Biol Chem,2002
4. The connecting segment between both epidermal growth factor-like domains in blood coagulation factor IX contributes to stimulation by factor VIIIa and its isolated A2 domain;Celie;J Biol Chem,2002
5. Region of factor IXa protease domain that interacts with factor VIIIa: analysis of select hemophilia B mutants;Bajaj;Thromb Haemost,1999
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