The H3antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteers-Reference-Cited by-同舟云学术

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The H3antagonist ABT-288 is tolerated at significantly higher exposures in subjects with schizophrenia than in healthy volunteers

Published:2014-05-22 Issue:6 Volume:77 Page:965-974
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Othman Ahmed A.¹²,Haig George³,Florian Hana³,Locke Charles¹,Gertsik Lev⁴,Dutta Sandeep¹

Affiliation:

1. AbbVie Clinical Pharmacology and Pharmacometrics; AbbVie; North Chicago IL USA

2. Department of Pharmaceutics; Faculty of Pharmacy; Cairo University; Cairo Egypt

3. AbbVie Neuroscience Development; AbbVie; North Chicago IL USA

4. California Clinical Trials; Glendale CA USA

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12281/fullpdf

Reference21 articles.

1. Deficit and nondeficit forms of schizophrenia: the concept;Carpenter;Am J Psychiatry,1988

2. Pathogenesis of schizophrenia: a psychopathological perspective;Owens;Br J Psychiatry,2005

3. Clinical constructs and therapeutic discovery;Carpenter;Schizophr Res,2004

4. Neurocognitive effects of antipsychotic medications in patients with chronic schizophrenia in the CATIE Trial;Keefe;Arch Gen Psychiatry,2007

5. Cognitive improvement after treatment with second-generation antipsychotic medications in first-episode schizophrenia: is it a practice effect?;Goldberg;Arch Gen Psychiatry,2007

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